Submitted by lac59 on Thu, 13/03/2025 - 16:08
"A 14-year study tracking NfL levels in people with the Huntington's Disease gene shows this tiny protein can signal disease progression many years before symptoms start. The longest follow-up study yet adds weight to NfL as a powerful tool for HD research."
The new paper on Huntington's Disease has been co-authored by Dr Zanna Voysey together with PhD student Natalia Owen. Co-authors from Clinical Neurosciences include Dr Maura Malpetti and Professor Roger Barker.
Read the full story on HD Buzz: Listening for Whispers: How a Tiny Protein Could Transform HD Research - HDBuzz - Huntington’s disease research news.
Read the new paper with all authors on PubMed: A 14-year longitudinal study of neurofilament light chain dynamics in premanifest and transitional Huntington's disease - PubMed
Keywords: Biomarker; Dementia; Huntington’s disease; Longitudinal; Neurodegeneration; Neurofilament light chain.