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Clinical Neurosciences

 
Read more at: ‘Disease in a dish’ study of progressive MS finds critical role for unusual type of brain cell

‘Disease in a dish’ study of progressive MS finds critical role for unusual type of brain cell

10 October 2025

Scientists have identified an unusual type of brain cell that may play a vital role in progressive multiple sclerosis (MS), likely contributing to the persistent inflammation characteristic of the disease. Read the full paper on Neuron: Integrated omics reveals disease-associated radial glia-like cells with epigenetically...


Read more at: Common diabetes drug and antihistamine could together repair MS damage

Common diabetes drug and antihistamine could together repair MS damage

26 September 2025

Early findings suggest a combination of metformin, a diabetes drug, and clemastine, an antihistamine, can help repair myelin – the protective coating around nerves, which gets damaged in multiple sclerosis (MS) causing symptoms like fatigue, pain, spasms and problems with walking. Funded by the MS Society and carried out...


Read more at: “promising news” but “early days” – Cambridge researchers respond to new Huntington’s gene therapy trial

“promising news” but “early days” – Cambridge researchers respond to new Huntington’s gene therapy trial

26 September 2025

On the 24 th of September 2025 a major breakthrough for Huntington’s disease was announced by a research team at UCL: a new gene therapy delivered directly to the brain that slowed disease progression by a reported 75%. But what does this mean for clinicians and patients? And what are the challenges for bringing promising...


Read more at: Maura Malpetti wins 2025 young European Researcher Award for Alzheimer’s research
Dr Maura Malpetti credit Cambridge University

Maura Malpetti wins 2025 young European Researcher Award for Alzheimer’s research

25 September 2025

Dr Maura Malpetti has won the 2025 European Young Researcher Award from the Fondation Recherche Alzheimer in France. This leading French foundation supports the advancement of research in Alzheimer's disease and related syndromes in France and beyond. To support this work, it founded its European grand prize awards...


Read more at: Raising awareness on Brain Injury in Cambridge

Raising awareness on Brain Injury in Cambridge

9 September 2025

This year, researchers at the Department of Clinical Neurosciences are raising awareness in Cambridge on traumatic brain injury research and safety in partnership with the Cambridge City Mayor. The campaign highlights the work of Professor Peter Hutchinson and his team. Peter is a specialist neurosurgeon and director of...


Read more at: Cambridge to host cutting-edge total-body PET scanner as part of nationwide imaging platform
Siemens Healthineers Biograph Vision Quadra Total-Body PET Scanner. Credit: Siemens Healthineers

Cambridge to host cutting-edge total-body PET scanner as part of nationwide imaging platform

2 September 2025

A new total-body PET scanner to be hosted in Cambridge – one of only a handful in the country – will transform our ability to diagnose and treat a range of conditions in patients and to carry out cutting-edge research and drug development. The scanner, funded through a £5.5m investment from the UKRI Medical Research...


Read more at: Cambridge-Nigeria research collaboration to advance hypertension imaging
Professor Ganiyat Oloyede visiting the Yusuf Hamied Department of Chemistry

Cambridge-Nigeria research collaboration to advance hypertension imaging

13 August 2025

Professor Ganiyat Oloyede, a leading expert in Medicinal Chemistry from the University of Ibadan, Nigeria, recently completed a research visit to the Molecular Imaging Chemistry Laboratory (MICL) in Cambridge. Her stay, from June 5th to 22nd, marks a significant step in a collaborative project with MICL Director, Professor...


Read more at: First ever mitochondrial disease treatment approved by NHS England

First ever mitochondrial disease treatment approved by NHS England

7 August 2025

The first ever treatment for a mitochondrial condition has been approved for use on the NHS in England in a major breakthrough in the fight against the disease. The National Institute for Health and Care Excellence (NICE) has announced the approval of Idebenone (Raxone) for the treatment of Leber’s Hereditary Optic...


Read more at: News - The Times: Tim Rittman features in UK Biobank project

News - The Times: Tim Rittman features in UK Biobank project

16 July 2025

Dr Timothy Rittman was featured in the Times on the coverage of the 100,000th person scanned for the whole body scanning project by UK Biobank. His lab have been using some of the first tranches of scanning data for research on Alzheimer's disease and rarer neurodegenerative disorders. Read the article mentioning Dr...


Read more at: Outlook for people with rare stroke condition has improved with the help of specialist care in Cambridge
The CADASIL clinic team (left to right) Amy Jolly, postdoctoral research associate, Natalia Owen, PhD student, Kate Rose, medical secretary and Professor Hugh Markus.

Outlook for people with rare stroke condition has improved with the help of specialist care in Cambridge

15 July 2025

Greater awareness and the availability of specialist care has helped to delay the average onset of symptoms caused by a rare genetic condition by around five years, according to a recent study. The condition causes early-onset strokes and increases risk of dementia, often affecting multiple members of the same family...