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Clinical Neurosciences

 
Read more at: Metabolic driver of Parkinson’s offers new target for treatment

Metabolic driver of Parkinson’s offers new target for treatment

30 April 2025

Researchers led by Dr Sung Min Son and Prof David Rubinsztein (UK DRI at Cambridge) have identified a key enzyme driving forms of Parkinson’s, and have shown how blocking it restores normal function in animal and cell models – offering a promising new drug target for the condition. In Parkinson’s, a protein known as alpha-...


Read more at: Stefano Pluchino receives Experimental Medicine Trial Award from the International Progressive MS Alliance

Stefano Pluchino receives Experimental Medicine Trial Award from the International Progressive MS Alliance

29 April 2025

This international award has gone to three development projects in Canada and the United Kingdom, which will each receive €100,000 to begin planning for future clinical trials. Dr. Stefano Pluchino’s team is one of three projects to have received funding for clinical trial development projects as part of the International...


Read more at: World-first trial indicates immunosuppression may help treat Parkinson's

World-first trial indicates immunosuppression may help treat Parkinson's

23 April 2025

A groundbreaking trial, led from Cambridge, has revealed that immunosuppressing medicines show promise for the treatment of Parkinson’s disease, according to results presented this weekend at the world’s most prestigious neurodegeneration conference AD/PD. This trial is the first to show that broadly suppressing the immune...


Read more at: Powerful new MRI scans enable life-changing surgery in first for adults with epilepsy
7T MRI Scanner

Powerful new MRI scans enable life-changing surgery in first for adults with epilepsy

25 March 2025

Scientists have developed a new technique that has enabled ultra-powerful magnetic resonance imaging (MRI) scanners to identify tiny differences in patients’ brains that cause treatment-resistant epilepsy. It has allowed doctors at Addenbrooke’s Hospital, Cambridge, to offer the patients surgery to cure their condition...


Read more at: First global pituitary study gives patients voice on research
Illustration by: jennyleonardart.com

First global pituitary study gives patients voice on research

20 March 2025

155 patients, carers and healthcare professionals across 14 countries identified their top 10 questions for researchers. Researchers from Cambridge and London have completed a study that is a world first of its kind and gives patients an important voice on future priorities. It was led by Angelos Kolias, Consultant...


Read more at: Prestigious MRC Fellowship awarded to revolutionize microglia metabolism research and find groundbreaking treatments for cognitive decline in multiple sclerosis

Prestigious MRC Fellowship awarded to revolutionize microglia metabolism research and find groundbreaking treatments for cognitive decline in multiple sclerosis

14 March 2025

Dr. Luca Peruzzotti-Jametti of the Department of Clinical Neurosciences, University of Cambridge, has been awarded a prestigious MRC Clinician Scientist Fellowship. This £2 million, five-year grant will fund research to fundamentally reshape our understanding of neuroinflammation and cognitive decline in conditions such as...


Read more at: Research news: How a Tiny Protein Could Transform HD Research

Research news: How a Tiny Protein Could Transform HD Research

13 March 2025

"A 14-year study tracking NfL levels in people with the Huntington's Disease gene shows this tiny protein can signal disease progression many years before symptoms start. The longest follow-up study yet adds weight to NfL as a powerful tool for HD research." The new paper on Huntington's Disease has been co-authored by Dr...


Read more at: In the news | BBC | Early dementia blood test trial begins

In the news | BBC | Early dementia blood test trial begins

19 February 2025

"A simple blood test designed to detect dementia decades before it develops is being rolled out across the UK as part of a "very exciting" new study. University of Cambridge scientists will use the approach to measure brain changes in people with dementia as an alternative to "more costly brain scans". It is based on...


Read more at: In the news | BBC | trial for rare disorder neuroferritinopathy

In the news | BBC | trial for rare disorder neuroferritinopathy

11 February 2025

"Samantha Denison, 58, has neuroferritinopathy, a rare disease that mainly affects a small number of families with roots in Cumbria. She is taking part in a trial to see if an existing drug, deferiprone, can remove the build-up of iron in the brain which causes the disease." Read more about Samantha's story and the DefINe...


Read more at: Deaf teen helps build VR therapy for hearing impaired youth

Deaf teen helps build VR therapy for hearing impaired youth

15 January 2025

"When it’s too noisy you can get overwhelmed and zone out. It can make socialising with friends very difficult and can be incredibly isolating." Kaitlyn is now hoping to help a generation of D/deaf children and young people thanks to her involvement in an innovative new virtual reality medical trial. Kaitlyn is a 20-year-...